FitnessDose

Showing posts with label human growth hormone. Show all posts
Showing posts with label human growth hormone. Show all posts

Wednesday, September 4, 2013

HGH Therapy - Adding Vitality to Your Life

Steroids have been controversial ever since these were introduced in the 1950s. Numerous news accounts, mostly on sports figures that tested positive for steroid use, continue to bring negative connotation on these substances. While it is true that some forms of steroids are banned, there are many which are legal (albeit restricted), including the Human Growth Hormone (HGH), also known as Somatotropin. Marketed as Real HGH, Somatropin or 191 Amino Acid Sequence HGH, the biologic drug is available in the US, Europe and other countries. hgh therapy

This HGH hormone is produced naturally in the human body by the pituitary gland and, as its name implies, is responsible for making cells grow bigger and divide more rapidly. HGH also facilitates inter-cellular amino acid distribution and conversion to proteins, which results in muscle build-up. Studies also show that somatotropin reduces carbohydrate usage in the cells and increase utilization of fats, resulting in a leaner body composition.

Humans make HGH throughout their lifetime; a steady growth from the early years until puberty when production of the hormone reaches its peak and the body experiences growth spurts. At the age of forty, the amount of HGH produced by the body starts to decline a phenomenon seen as the main cause of reduced body functions and frailty that comes with old age.

At present, HGH is medically indicated for the following conditions: growth hormone deficiency in adults, children with short stature or kidney failure, and people with HIV and AIDS - to counteract the muscle wasting effect of these conditions. In the US, use of HGH as an anti-aging treatment is prohibited, though in a report last year, CNN found that prescriptions for HGH treatment are on the rise, even if its legal status is fuzzy.

In adults, use of HGH had been shown to increase metabolism, physical and mental energy, muscle mass, libido and bone density as well as normalize cholesterol levels and reduce body fat. Some of the side effects associated with HGH include swelling in arms and legs, arthritis and carpal tunnel symptoms, muscle pain, diabetes and abnormal growth of bones. Weighing the benefits one gets from HSH against the common side-effects, a growing number of endocrinologists have recognized that in many cases, the advantages far outweigh the possible side-effects, particularly for people whose lifestyle has been greatly curtailed as a result of the hormone deficiency. There are many documented instances wherein patients report generally greater signs of vitality, better health and well-being after taking the hormone.

In the US, body builders and other people with active lifestyles routinely use HGH procured either by prescriptions or online purchases. Obviously, these people see the lean muscle development and fat-burning effects of the hormone greater than the risks associated with it. Other important factors that weigh heavily in favor of HGH are its ability to heal muscle - even cartilage- injuries quickly, and the fact that it is undetectable (for now) in current drug-testing tests a boon for athletes who are required to undergo these tests. For years, bodybuilders have known that combining the hormone with testosterone drugs brings better results well-defined muscles, heightened endurance and strength.

While selling of the injectable HGH is restricted in the country, a lot of online suppliers from abroad can ship the drug to US residents without any complications. Usually, the hormone is taken with other performance-enhancing steroids which are also supplied by the online stores.

Wednesday, January 9, 2013

Nolvadex and Clomid (estrogen receptor antagonists)

Estrogen receptor antagonists, more simply referred to as anti-estrogens (though this term is often loosely applied to all estrogen maintenance drugs), are drugs that block estrogens from exerting activity in the body. This is actualized by the ability of a particular substance to bind to a segment of the estrogen receptor, yet not activate it. This in turn prevents other estrogens from binding and activating the same receptor site. In a clinical setting an estrogen antagonist, most prominently the drug tamoxifen citrate (sold under the brand name Nolvadex) is typically used as the first line of defense during advanced breast cancer therapy. Its use can efficiently deprive estrogen responsive cancer cells of necessary hormone, allowing a high rate of response in patients with such forms of cancer.
Stronger agents such as aromatase inhibitors (discussed below) are usually a second choice, substituted when conventional antiestrogen therapy fails to elicit the desired response.
A drug like tamoxifen is preferred over other agents as the first course of breast cancer treatment for a number of reasons, most due to the fact that that it is both extremely effective yet does not inhibit the actual formation of estrogen in the body. Among other things, this may allow Nolvadex therapy to be somewhat more comfortable for the patient. Although many women (particularly pre-menopausal) seem to suffer menopausal-like side effects with virtually all estrogen maintenance drugs, estrogen antagonists are often somewhat more tolerable than agents that block the synthesis of estrogen. In fact the activity of tamoxifen is itself variable, such that in certain target tissues it may actually act as an agonist (activator) of the estrogen receptor. It therefore does not completely diminish the biological activity of estrogens, though it does considerably reduce it nonetheless.
It is also well understood in medicine today that estrogens play a supportive role in the cardiovascular system. For example, studies show that a rise in the estrogen level (as in post-menopausal estrogen replacement therapy) is typically linked with a reduction in LDL (bad) cholesterol, and a rise in HDL (good) cholesterol. The ability of tamoxifen to act as an estrogen agonist in the liver likewise gives it what may be its most welcome property, namely that it exhibits an estrogenic, rather than antiestrogenic, effect on blood lipid (cholesterol) values. As a 1998 study by the Department of Clinical Oncology in the Netherlands Cancer Institute shows, during long-term treatment with tamoxifen (6 months) a lowered LDL cholesterol level, and significantly elevated HDL cholesterol level and HDL-C/total-cholesterol ratio may result. This trend should reduce an important risk factor for heart disease, obviously a welcome effect during treatment.
For the steroid-using athlete already faced with negative alterations in lipid profiles, such an effect could obviously an important consideration.
Clomid (clomiphene citrate) is very similar in structure to Nolvadex, both drugs being classified as triphenylethylene compounds and used clinically for similar purposes (breast cancer as well as female infertility treatment). As well as we see with Nolvadex, Clomid is a partial agonist/antagonist of the estrogen receptor depending on the target tissue in question. Although athletes most commonly think of Clomid as a testosterone-stimulating drug only (another effect of antiestrogenic compounds), to be used at the conclusion of steroid treatment, its activity in the human body is not at all dissimilar to Nolvadex. It should likewise be thought of not as a drug with its own niche of use, but instead as another efficient remedy for gynecomastia similar to Nolvadex (with the related ability to support the release of testosterone). It could clearly replace Nolvadex as a preventative measure against gynecomastia during cycles with aromatizable steroids without noticeably altering the level of effect received, just as Nolvadex can be used effectively to increase the synthesis of testosterone in the body at the conclusion of steroid use.

Wednesday, June 27, 2012

HGH Human Growth Hormone Effects in Bodybuilding

For young athletes under 27 years, human growth hormone (HGH) acts as a powerful anabolic, positively influencing on increase in body size. This applies to length and thickness of the bones, as well as the amount of muscle. In later years the effect of growth hormone is less noticeable, but its ability to some extent, increase muscle mass, as well as significantly reduce body fat, used in bodybuilding.

Effect of growth hormone

    enhances protein synthesis, provides a steady but slow increase in muscle
    strengthens the bone and connective tissue
    improves metabolism
    increased use of fat for energy needs
    increases in liver glycogen
    at speeds up healing of injuries and rehabilitation

The level and stimulators of growth hormone
Receiving a command from the hypothalamus, the pituitary gland produces growth hormone, which is getting into the blood reaches the liver and converted it into the main working material - somatomedin. Number of growth hormone production increases from birth and reaches a peak of about 21 years, with the same slow down in life. During the night may take place before the 10ti releases the hormone into the bloodstream.
For effective training in bodybuilding, prevent injuries and fatigue, normal growth hormone levels is vital. Even better - if we can improve it.

Stimulants
- Good night's sleep
- The state of stressful
    exercise stress
    pain
    a sharp temperature drop
    Hunger - sleep on an empty stomach is useful in many ways

- The use of protein food. The greatest influence on the production of growth hormone has an intake of protein such as arginine (pork, cheese, cottage cheese, nuts).

Obstacles for the development and effectiveness of HGH can be:

- Exhaustion of the nervous system
- Violations of the liver
- High levels of cortisol
- Receipt of carbohydrate foods