FitnessDose

Tuesday, July 8, 2014

STEROIDS HALF LIFE AND VERSUS HALF LIFE

Anyone new to steroids may be wondering what Steroid half life means, even some experienced steroid users may also be wondering what half-lives means. So here in simple terms you can read and hopefully understand all about steroid half life's and what this term means.

Basically every drug has a half life, steroids included. If for example, you were to inject 1000mg of testosterone cypionate once weekly, for 10 weeks, how would you know when you were "off"? Would you be "off" when you had finished your last dose? You would be able to calculate this from the half life of testosterone cypionate. The half life of testosterone cypionate is around 12 days. This means that 12 days from your last shot of 1000mg of testosterone cypionate (Time to start PCT? You decide.), your blood levels of testosterone cypionate will contain 500mg of the steroid. Another 12 days from then, i.e. 24 days from last dose, your blood levels will contain 250mg of the steroid. This amount then keeps halving every 12 days. At 48 days (almost 2 months) from your last dose, your blood levels will still contain 67.5mg of testosterone cypionate.

Therefore you can clearly see that when you finish your cycle, even though you are not putting any steroids into your body, you may think that you are now "off", however you still have, and will still have for some time after your last dose, "active" blood levels of the steroid. Therefore you can plan what to use, how long for, and how long off your cycle, based on these half life's.

Below a list of half-life's of the most commonly used steroids, esters and ancillary compounds.


Oral steroids Drug Active half-life

Anadrol / Anapolan50 (oxymetholone) 8 to 9 hours
Anavar (oxandrolone) 9 hours
Dianabol (methandrostenolone, methandienone) 4.5 to 6 hours
Winstrol (stanozolol) (tablets or depot taken orally) 9 hours
Depot steroids Drug Active half-life
Deca-durabolin (Nandrolone decanate) 14 days
Equipoise 14 days
Finaject (trenbolone acetate) 3 days
Primobolan (methenolone enanthate) 10.5 days
Sustanon or Omnadren 15 to 18 days
Testosterone Cypionate 12 days
Testosterone Enanthate 10.5 days
Testosterone Propionate 4.5 days
Testosterone Suspension 1 day
Winstrol (stanozolol) 1 day


Steroid esters Drug Active half-life

Formate 1.5 days
Acetate 3 days
Propionate 2 days
Phenylpropionate 4.5 days
Butyrate 6 days
Valerate 7.5 days
Hexanoate 9 days
Caproate 9 days
Isocaproate 9 days
Heptanoate 10.5 days
Enanthate 10.5 days
Octanoate 12 days
Cypionate 12 days
Nonanoate 13.5 days
Decanoate 15 days
Undecanoate 16.5 days


Ancillaries Drug Active half-life

Arimidex 3 days
Clenbuterol 1.5 days
Clomid 5 days
Cytadren 6 hours
T3 10 hours


Active Life versus Half Life

The confusion comes from the 2 terms being used synonymously when they should not be. "Half-life is not a reference for the total time a drug will be found active in the body. It may take several half-lives before the drug is completely inactive."

Half-life: The period of time required for the concentration or amount of drug in the body to be reduced to exactly one-half of a given concentration or amount.

Example: The half-life of anavar is 9 hours+/- (9 hours after oral administration of 50 mg of anavar, 25mg is still present in the body).

Active life: Refers to the period in which the amount of a drug in the body is enough that it will still produce the desired effects for which it was administered. Or conversely, inhibit natural recovery of normal bodily function. It is dose dependent.

Example: The active life of 1,000mg of testosterone decanoate would be more than one month. At day 30 after injection, 250mg or more of this drug would still be present in the body.

Tuesday, July 1, 2014

Running With Monsters: Test Prop, Tren Ace and Winny

The purpose of this article is to educate and help support the use of a very powerful cycle; Test prop, Tren ace, and Winny. The correlation of short esters, the monster that Tren is, and the drying effects of Winny make this cycle great for a summer shredder. Before we get into the cycle itself, lets take about the compounds separately.

TESTOSTERONE PROPIONATE:

When it comes to compounds and stacking testosterone is king. It is the foundation which cycles are built upon. Running any compound without the use of testosterone will leave you with hormone levels similar to a females. Testosterone propionate is a fast acting ester. With a 3 day half-life, it requires a more frequent dosing schedule to reach and maintain stable blood levels. Ideally, prop should be injected every day, but every other day injections have been deemed acceptable (but not optimal). Dosages for testosterone prop range from a minimum of 50mg every other day up to 150mg every other day (some may choose to go higher, but must understand that high dosing should be reserved for very advanced bodybuilding).   Estrogen side effects are an issue with prop. Though the peak values of prop are usually lower than those of longer esters, it hits you much faster. If you are sensitive to aromatization its recommended you take the necessary precautions with an SERM or AI.

TRENBOLONE ACETATE:

Trenbolone acetate, or tren ace as its more popularly known, is by far one of the most powerful injectable anabolic steroid. It is considered five times more powerful both anabolic and androgenic properties than testosterone. Tren is a derivative of testosterone. The 19th position of testosterone was altered to give us Tren. Being a 19-nor, tren is up there on the list in terms of liver toxicity. Though tren does not aromatize, it will cause a rise in progestin levels. Proper anti-estrogen/progestin drugs should be used (cabergoline or prami would be best). Tren has a very high binding affinity to the androgen receptor. It also raises igf levels in a way no other compound can (secondarily). One of the most amazing traits of Tren is its ability to increase feed efficiency. The drug allows the body to utilize more of the macro and micro nutrients you ingest, allowing you to eat less and get more out of your nutrition. Tren is well known as a recomp or hardening compound. It has been hailed as the “devils juice” due to the side effects of insomnia, over-active sweat glands, and changes of temperament (it’s the only steroid to show true changes in temperament). Supplementation of thyroid hormones should be used with tren since it has shown to reduce thyroid function. The acetate ester is one of the shortest esters popularly used in the bodybuilding community. Having a shorter ester than propionate (by about one day) its highly recommended that tren ace be injected daily. The ace ester allows for quick absorption of the compound if side effects occur and the user has to discontinue the drug. Since tren and testosterone fight for the same androgen receptor, its recommended that tren take the higher dosage in a cycle while testosterone takes on more of a maintenance dosage. The proper dosage of Tren ace should be no more than 50mg ed for beginners. Once you get a feel for how much you can tolerate you can slowly raise the dosage of Tren while keeping eyes on any sides that may come of it.

Winstrol (WINNY, STANOZOLOL):

Winstrol has been used by bodybuilders as a cutting steroid for years. Its known for its strong drying properties, making it ideal for those last few pounds of water weight that would usually be stubborn. It is a 17aa compound. It has been altered to survive the first pass through the liver which also makes it highly liver toxic (like most oral steroids), so the use of the injectable version is recommended. Winny also does a great job of lowering SHBG levels, keeping the body from robbing you of free testosterone. The effective dosage of winny is 50 to 100mg daily but cycles should be kept under 8 weeks due to the high toxicity of the compound.

THE PROPER TEN WEEK CYCLE

The up side of running a cycle with short esters is that you can run it shorter than a long estered cycle. Justifiably, you shouldn’t need to run this cycle more than 10 weeks (though you can go as short as 6 weeks).  I will set this cycle up for an every other day injection schedule to make it easier on the user. Remember that this is a beginners cycle for these compounds.

    Testosterone Prop 50mg eod week 1-10steroid muscle
    Tren Ace 75mg eod week 1-10 (dosage can be raised up to 150mg eod if the body allows without adverse side effects)
    Winny 50mg ed week 2-10
    Prami for progestin control should start the second week of tren at .25mg once a week (then up to twice a week if necessary) Keep in mind prami can make you feel sick. Its recommended to take it at night before you sleep. Week 2-10
    HCG 250iu twice a week week 1-10
    T3 25mcg ed week 1-10

PCT - Post cycle therapy should start one week after your final injection and last for 4 weeks

    Clomid 100/50/50/50
    Nolvadex 100/100/50/50

Tuesday, June 24, 2014

Anadrol 50 - Increase Your Bulking Abilities

It’s time for a serious bulk cycle. You just competed in the bodybuilding open division for the first time, and let’s be honest- you just had your rear end handed to you by guys carrying a lot more muscle. It’s time to buckle down and spend a solid 9 months adding muscle to your frame. You’ve had your post-show food binge. You already retired then un-retired. You’ve spent the last 2 weeks moping with your face in a pizza box mulling over your next step. You gave your body a rest and now it’s time to come back, both barrels firing. Let’s add some mass!

This time, you’re going to do it right. You’re going to run a cycle using the very toxic, and very powerful Anadrol 50. It’s well known in steroid circles that the most effective steroids also deliver the most side effects, and you’re prepared for that. Let’s learn more about Anadrol and see if you’re ready for it.

Anadrol is one of the most powerful steroids. It will certainly help you gain lean muscle mass, that goes without saying. Your appetite will skyrocket, allowing you to eat more food. Your protein synthesis will increase, meaning you will be able to use more of the protein in your diet for muscle-building purposes. Your red blood cell count will increase, making you stronger and allowing you to possess more stamina. You’ll retain some water – which can be a good thing or a bad thing. In a way, this is good because it means you will be cushioning your joints, much larger and stronger, and able to move more weight, which will lead to a gain in muscle mass. At the same time, this water retention can also cause you to look and feel bloated. There are also the side effects of acne and potential liver damage. You don’t want to use Anadrol for your entire off-season. Rather, two small cycles of 8 weeks separated by a 12 week gap is preferable.

Anadrol has been out for almost 50 years, and remains popular despite all of the innovations in steroids that have arrived during this time. It is an oral drug, and is only active in the body for about 16 hours. It can be detected in steroid tests up to 2 months after use, a fact that should be considered when planning your pre-contest stack or participating in any tested powerlifting event.

Anadrol should be stacked with injectables in order to make the most possible gains in a short amount of time. Adding it to a cycle of testosterone and Nandrolone will leave you feeling superhuman, and will add some serious mass to your frame. It works in just about any bulking stack, so long as you give yourself enough food, training and rest to make the most of it. Anadrol is a fairly safe drug, despite the toxicity warnings, as long as it is used in moderation and breaks are taken. Give it a shot this off-season if you are very serious about gaining some new muscle mass.

Thursday, June 12, 2014

Recommended Recovery Time Between Anabolic Steroid Cycles

The first factor is that recovery of the HPTA (hypothalamus, pituitary, and testicular axis) from one cycle should always occur fully before starting the next.

Where an anabolic steroid cycle is very short, such as only 2 weeks, steroid cycle recovery can be almost immediate. Well-planned, moderate length steroid cycles, such as only 8 weeks, often allow recovery in a time frame such as only 2 weeks.

Long steroid cycles, such as 12 weeks or longer and especially 14 weeks or longer, or poorly planned cycles often have very protracted recoveries.

So first, regardless of what is written below with regard to timing, you should wait until natural testosterone production, without aid of any drug, is back to midnormal levels or better.

Other than this, the time between steroid cycles should be related to duration of anabolic steroid use, including time of clearance after the last injection. Another way of looking at that is the balance between the number of weeks that anabolic steroids are used versus the number of weeks that no steroid is being used.

There really are no black/white cutoff values that anyone can give. Time off versus time on is a gradually sliding scale.

Broadly speaking:

    Being “off” twice as many weeks as being “on” is entirely conservative for most who are seeking to build muscle, and absolutely can give great results. Really the only reason to be more conservative than this is if wishing only to maintain.
    Being “off” about as many weeks as being “on” is moderately aggressive. When the cycles are well-planned, there’s generally no problem with this and, of course, this can give somewhat faster results than the above.
    And being “off” only half as many weeks as being “on” is about as aggressive as I recommend for the health conscious person. Proper recovery should of course be verified, and blood tests become more important at this frequency of use.

So there’s no one answer, but the above general description has over time proven helpful for many to decide where they wanted to be.

Tuesday, June 3, 2014

Anabolic Steroids and Estrogen Control for Maximizing Fat Loss


Prior to proper estrogen control with antiaromatases such as letrozole or Arimidex, care ordinarily would be taken in cutting cycles to limit the amount of aromatizing steroids used. Particularly, testosterone and Dianabol would be limited, if used at all. So this resulted in their having a reputation of “not being cutting steroids.”

There were two factors involved here. First, estrogenic bloating could to the eye be confused with fatness. And second, abnormally high estrogen levels can make fat loss more difficult.

Where estradiol level is controlled with an antiaromatase or with a suitably balanced combination of steroids, then these are not issues, and testosterone becomes about as good for cutting as anything else. Dianabol also can aid fat loss quite well.

Under suitably balanced is considered a combination of aromatizing and non-aromatizing steroids where the total amount is sufficient for the desired anabolic effect, and the amount of aromatizing steroids is suitable to yield only normal estradiol levels. This typically would be between 100-300 mg/week, but good results can often be had with more than this, depending on the individual. Where for example a person already knows from experience that he suffers little or no noticeable adverse estrogenic effect from say 500 mg/week of testosterone, then that amount certainly can be included in a cutting cycle without need of an antiaromatase. But another person might even get gyno on 250 mg/week testosterone.

It’s certainly possible that some fat-loss differences remain between anabolic steroids, but even so this may only be dose related. For example, 50 mg/day trenbolone acetate is certainly better for cutting than 50 mg/day testosterone, but is it better than 150 mg/day testosterone? Probably not.

Basically, it’s not necessary to seek out particular anabolic steroids for fat loss. Make the choice based on achieving desired positive effects with minimization of the side effects of personal concern, which can vary according to the situation.

Wednesday, May 28, 2014

The Myth of Anabolic Steroids for Bulking or Cutting

The myth that there are various anabolic steroids specifically for ‘bulking’ and/or specifically for ‘cutting’ must be addressed. It first must be made perfectly clear that Anabolic steroids do not directly burn fat, as they instead simply increase nutrient partitioning. Nutrient partitioning is defined as the effect of directing/shuttling ingested nutrients, vitamins, and minerals towards muscle repair and muscle growth to a large degree – so much so that fat storage is either completely avoided or dramatically reduced. Anabolic steroids do not possess any direct effects on fat metabolism that would result in dramatic changes. It is understood that anabolic steroids do interact with androgen receptors on fat tissue to initiate lipolysis (fat breakdown), but this does not occur to any significant degree.

The ‘fat burning’ properties commonly associated with anabolic steroids stem from the aforementioned extreme level of nutrient partitioning they exhibit. Some types of steroids exhibit this at a far greater degree than any other anabolic steroid, especially anabolic steroids such as Trenbolone. Even Testosterone does this, where cases have been observed whereby an individual engaging in their first-ever cycle of Testosterone results in the gaining of lean mass, and a reduction of varying degrees of body fat percentage.

Of course, the most prominent detail to be reminded of is the fact that results are 100% dependent on the individual’s nutrition and training. Different types of steroids merely serve to amplify the efforts and hard work that the nutrition and training aspects have properly established. For example, if an individual’s primary goal of fat loss is desired, then the individual’s nutrition must reflect that by either engaging in a caloric deficit or some sort of nutritional plan that favors fat loss. Although various anabolic steroids might also exhibit effects and properties that favor bulking or mass gaining cycles, such as Dianabol or Anadrol for example, it does not mean that they cannot be utilized for the purpose of fat loss or cutting as well. It is the individual’s diet that will determine whether he or she experiences fat loss or muscle gain. The decision for most athletes to refrain from the use of compounds such as Dianabol for fat loss rests solely on the fact that Dianabol exhibits Estrogenic activity that results in water retention and bloating, resulting in the puffy, bloated, and soft look to the physique that is not desired during fat loss phases. With that being said, one could easily work around this limitation with the inclusion of an aromatase inhibitor, but the general rule remains: nutrition and training determine results, not the types of steroids used.

Tuesday, May 20, 2014

Melanotan 1 and 2 - Two Wildly Popular Peptides with Different Benefits

 In the early 1980s, University of Arizona researchers hypothesized that they could cure various types of skin cancer by inducing the body's natural pigmentary system to create a protective tan before UV exposure. So they synthesized a naturally occurring peptide called Melanotan to accomplish this task. Scientists have since had a tough time using Melanotan to battle skin cancer, but they've found some more reliable uses for this peptide.

melanotan1 Its most immediate use is as a sunless tanning agent, making the peptide very popular among bodybuilders. Scientists have also discovered that Melanotan can be very effective at curing sexual dysfunction. But it's worth mentioning that there are two types of this peptide - Melanotan 1 and 2 - and they each have their own individual benefits and traits. That said, let's answer some common questions about these differences and discuss side effects, dosage, female usage and more.

What is the Difference between Melanotan 1 and 2?
Melanotan 1 or "Melanotan I," when referring to tanning, is a drug currently in trials for light-affected skin disorders. Melanotan 2 is also a drug that's been developed as a skin-tanning agent, and it's popularized as a treatment for sexual dysfunction as well. It is mostly agreed that Melanotan 1 has less side effects, although it's slightly less potent.

What Side Effects are Possible?
Those who've used Melanotan have reported that both versions can cause nausea and facial flushing. Melanotan 2 has also been known to cause new freckles and painful erections. Many researchers reported zero side effects when these drugs are used correctly and when they come from a quality source.
This is why its important to buy only from trusted places like buyusapeptides.com, which are made in the USA, are pure, and are the highest quality on the market.

Is this Safe to use on Females?
Absolutely. Melanotan is not a hormone whatsoever and is safe to use on both female and male sexes. And since Melanotan may have skin cancer-fighting properties, it can allow one to spend more time tanning without fearing UV rays as much.

How to mix?
Simply mix with bac water slowly, then store in fridge.

What is the Dosage?
Melanotan 1 shouldbe dosed 1mg per day for a week and then a maintenance dose of 2-3X per week. Thereafter, it is recommended taking this peptide before tanning. Melanotan 2 should be dosed at half an mg per day for a week, and then reduced to a quarter mg twice a week. These are merely average dosages, and one should always research what dosage will be best in one's own circumstance.

How long until you notice results?
Usually one will notice results within 1-4 weeks. New freckles may appear, however, this is nothing to be alarmed about.

Does Melanotan wear off? If so, when will it wear off?
Melanotan should be cycled on and off and, yes, the tan will fade away over time once you cease use.