Why Bodybuilders Use HGH And Peptides

GHRP-2, is a synthetic, hexapeptide that has some very potent properties. It is in the class of growth hormone releasing peptides (GHRPs), which act on the hypothalamus and the pituitary gland, to release growth hormone, by appearing through the endogenous ghrelin receptor. It is considered one of the few healthcare means that can be able to reverse the aging effects in adults who are deficient of the growth hormone.

GHRP-2 is known to encourage appetite and hunger. It does this by stimulating the release of Ghrelin, which is also a peptide observed in the stomach, that advertises urge for food and gastric emptying. GHPR-2 is also used for a range of other medical issues, which include, correcting low growth hormone production, and also promoting excess weight gain in the abnormally thin individuals.

GHRP user may report strength raise and improved muscle mass. This is along a much better overall sense of well being and decreased body fat. Neurons are also affected in the same method as they would be by steroids, causing a significant strength raise. For someone who has previously used artificial development hormone, slowing the body's natural production of the same, this peptide can be used to activate the natural production of this growth hormone.

This peptide is also a very suitable compound to use if one is nursing and rehabilitating injuries. It has been shown, clinically, to have a very good effect on connective tissues and tendons regeneration and strengthening. Depending on one's goals, a person may use between 100 - 600mcg per day. For instance, a person looking for some slight raise in sleep quality, or joint and tendon improvement, may stick towards the lower end of this dosage amount. Alternatively, a person seeking to use this peptide for its mass and muscle building effects may ramp up the dosage considerably.

Other benefits of using GHRP-2 include improved sex dr and desire, stomach fat decrease, enhanced energy and vitality, improved skin elasticity and lines elimination. There is also boostd endurance, heart strengthening, enhanced immune system, improved eye sight and vision, increased protein synthesis, enhanced bone density as a consequence of boostd lime scale retention (which also increases bone strength and mineralization), reduced glucose uptake in the liver organ, better liver glucogenesis, and contribution in the direction of pancreatic islets maintenance and function, among others. You can get peptide GHRP-2 online at http://www.genezameds.com/hgh-peptides-c75/ghrp-2-5mg-p430 GenezaMeds.com - we provide the bodybuiding and performance enhancing community top of the line service with products and reliability that you can trust.

Peptide Hormones: Insulin

Insulin is produced in the beta cells of the pancreas from a larger peptide called preproinsulin. Endogenous insulin has a half-life of three to five minutes and the pancreas secretes about 40 to 50 units of insulin per day in normal adults. Insulin secretion is stimulated in response to feeding with glucose being the strongest stimulator. Insulin binds to a cell surface receptor resulting in increased glucose and amino acid transport through the cell membrane and glycogen and lipid synthesis and storage. This is accomplished through the increased movement of Glut4 molecules to the surface of the cell membrane. Glut4 is the main transporter of glucose across cell membranes into cells. Insulin also binds to the type 1 IGF receptor which results in growth stimulating effects in muscle cells.

Insulin is the main “storage” hormone and is very anabolic as well as anti-catabolic. In addition to increasing glycogen and lipid synthesis and storage, insulin also promotes protein synthesis in skeletal muscle and promotes glycogen storage by increasing glucose transport in skeletal muscle cells.

Insulin and insulin syringes are available in many states without a prescription making insulin a more available anabolic hormone than AAS. That being said, the dangers of insulin are immediate and potentially deadly. Insulin can produce in a state of severe hypoglycemia that can result in coma or death with a matter of minutes. In addition, insulin resistance will occur over time in healthy individuals using insulin. While this risk is down-played by users and on boards discussing insulin, it should be considered a very real risk. Though insulin is highly anabolic in skeletal muscle, it is also very anabolic in adipose tissue. This can result in increases in body fat, especially when used in high doses on its own. Often insulin is combined with growth hormone to take advantage of growth hormone’s fat burning ability and to combat the decrease in insulin sensitivity with GH. IGF-1 is sometimes combined with insulin (and GH) but this increases the risk of hypoglycemia.

Anabolic Steroid Basics for Beginners

Esters:
You must understand esters. Esters are attached to AAS compounds. The ester acts as a kind of time releasing vehicle. Esters are broken down in the blood stream and thus the AAS compound is freed. Long-acting esters slowly break down, and fast-acting esters break down more rapidly. Half-life describes this occurrence.
Common Ester names in no particular order:
 Enanthate
 Cypionate
 Decanoate
 Phenylpropionate
 Propionate
 Isocaproate
There are blends, or mixtures of tests each with their own ester. These are mutli-esterified. An example is Sustanon 250, Omnadren 250, and Aratest.

Hypothalamic-Pituitary-Testicular Axis (HPTA):
Secondly you must understand the Hypothalamic-Pituitary-Testicular Axis and the affect Anabolic Androgenic steroids has on your HPTA. The use of AAS has a negative affect on your HPTA, which I'll put in simple terms. For a detailed explanation see the following link:

The body is always looking to establish homeostasis, a balance in the body. Upon the introduction of AAS to the body, you begin to reduce your own production. Some AAS compounds are harsher to your HPTA and shut your natural production down hard. A rebound from this shutdown is taxing on the body upon discontinuing use of AAS. Other compounds must be used to help the body return to homeostasis.
The compounds that are harsh on your HPTA will also be harsh on your libido; your sexual drive, and for men can result in a limp penis.
Such compounds that are harsh on the HPTA are:
Trenbolone (fina)
Deca-Durabolin
It is therefore, advisable for at least the sakes of sex, to keep Testosterone as a base for any AAS cycle.

Testosterone as a base:
There are limits to the length of cycle use. When you being AAS use, it takes time for the body to 'swap' its natural testosterone with the synthetic compound. The times vary with the particular ester used. However a short AAS cycle will most likely only result in a shut down of HPTA and not leave the body exposed to the synthetic testosterone long enough for positive gains. Too long of a cycle, and your suppressed HPTA will have a harder time recovering.
Further, the body can develop more or less immunities to AAS on cycles ran too long and cycles ran at too high of a dose.
Secondly, the body has limits for how much it can grow. A longer, higher dosed cycle will not be more effective simply because of the body's tolerance and limited ability to grow.
My own guideline for a first and second time user is any cycle ran less than 8 weeks is too short; any cycle ran longer than 15 weeks is excessive. 10-14 weeks is a good range for a first and second time user.

Estrogen:
Estrogen levels will be elevated during the use of AAS. Remember Homeostasis. Application of either anti-estrogen or anti-aromatizer.

The body has AS receptors and estrogen receptors. Your goal in using AAS is to flood the AS receptors. Your goal is not to flood the estrogen receptors.
How an anti-estrogen works is that it attaches itself to the estrogen receptors so that estrogen will not. Therefore the estrogen remains free floating in your blood stream but unable to leech onto the receptors and take action.
How and anti-aromatizer works is that it prevents the aromatization of steroids. It prevents the compounds conversion into estrogen. This however has the ability to weaken the effect of the steroid compound.
Zero estrogen is not desirable. Some estrogen is necessary, but too much can cause complications such as gynocomastia (man boobies) and water retention to name a few.

Common side effects while on Anabolic Steroids:
Users may experience a number of side effects due to increased synthetic testosterone levels as well as due to increased estrogen levels.
 Cardiovascular complications: High blood pressure can result from use of AAS and with heart problems should seek medical consultation. Combined water/sodium retention and the fact that steroids actually can elevate the cholesterol and triglyceride levels gives explanation to this condition. It is also why some athletes experience a reduction in stamina.
 Acne may result from AAS use, but can be combated a number of ways that should be researched.
 Aggression may also increase while on AAS, however some experience this aggression during high exertion activities, and will otherwise feel somewhat lethargic. Feelings of lethargy, sleepiness throughout the day while on AAS may result. This will be largely affected by the amount of physical activity performed throughout the day.
 hair loss on the scalp can occur. This condition, as with the others, is dependent on the individual. Certain individuals predisposed to premature hair loss may be at a greater risk for this side effect.
 Hair gain, or activation of hair follicles on the body may also occur. Hair follicles on the chest, back, arms and other places may be stimulated.
 Certain steroids are I 7-alpha alky-lated and are toxic to the liver. It is important to note this and limit intake of foods and beverages that will also be strenuous on the liver.
 As previously noted, AAS use will result in a reduced testosterone production, a decreased spermatogenesis, and in some cases testicular atrophy. The degree of suppression depends on the duration of the steroid intake, the administered steroid, and the dosage of the steroid
 Most steroids cause a water and electrolyte imbalance in the body This results in an increased storage of water and sodium which further results in a swelling of tissue (edema)
 Gastrointestinal symptoms such as epigastric fullness, diarrhea, nausea or even vomiting may result and are associated solely with the use of oral, I 7-alpha alkylated steroids. The oral compounds can be administered with food to reduce these side effects.
 Feminization may result in males if estrogen levels are not kept in check. The most popular feminization side effect of estrogen is gynocomastia.
 Females may experience masculinization effects.
 Kidney complications: The kidneys are under more strain during steroid intake. They are involved in the filtration and excretion of toxic by-products. A high blood pressure as well as variations in the water and electrolyte balance of the body can lead to long-term changes in the kidney's function.
There may be more side effects not listed. All side effects should be researched and understood. There are ways to alleviate some of the symptoms. Remedies and counter-actions should be researched before use of AAS.

Testosterone the Only Anabolic Steroid In a First Cycle

It is a well-known set-in-stone rule that Testosterone is such an essentially important hormone that it must be included as the primary base compound in every single cycle as either a primary anabolic compound, or at the very least as a supportive compound in the role of TRT. A ‘primary anabolic compound’ is defined as a compound within a cycle that acts as one of the primary contributors to muscle accrual, and must usually be run at supraphysiological bodybuilding doses to do so.
The same concept runs true in the sense that it is undesirable to stack multiple Anabolic Steroids in the very first cycle an individual will engage in. The issue with stacking compounds in a beginner cycle rests in the fact that it is quite possibly a very dangerous practice where unknown reactions are concerned. An individual who is a beginner that has never before utilized anabolic steroids (or has never engaged in cycle up to this point in their lives) would be unsure of what to expect in terms of effects, side effects, and experiences upon first use. Considering the massive amount of misinformation and over-exaggerated propaganda in regards to anabolic steroids by the general public, this can be quite concerning for a novice anabolic steroid user who is beginning to tread on unfamiliar waters. It then stands to reason that if a stack of multiple anabolic steroids are run in a first-time beginner cycle, and the individual reacts in a very negative fashion (or begins to experience very undesirable side effects), there is no possible means for this individual to narrow down and determine which of the multiple stacked compounds is the culprit for the bad reaction. There might even be multiple compounds exhibiting such an undesirable effect, and there might even be two or more anabolic steroids that would never exhibit such an effect without the synergistic interconnected effects with other compounds in the stack. One can easily see how this could easily become life-threatening if a particular reaction were to be a very serious mortal reaction, such as an allergic reaction, for example.

What Are The Risks of Leaving Testosterone Out of Every Cycle?

In the case of the utilization of Testosterone as a base essential compound in every single cycle, the idea of running a cycle that does not include Testosterone (or is an oral anabolic steroid only cycle) is, simply put, a very bad idea. Without any form of Testosterone present (endogenous or exogenous), the body will be unable to maintain those normal physiological functions that are controlled and governed by Testosterone itself.  Many other analogues and derivative anabolic steroids, such as Trenbolone for example, might perhaps be several times as anabolic as Testosterone (in Trenbolone’s case, it is five times the strength of Testosterone, which is extremely impressive). But these attributes and greater anabolic strength increases are all the advantages that the majority of these compounds have going for them. For example, as previously mentioned, Trenbolone is a very strong anabolic steroid – the strongest conventionally and commercially available anabolic steroid in existence – with absolutely no Estrogenic effects and very strong anabolic effects.  However, it does not serve as a proper androgen for normal physiological function within the body. ‘Normal physiological function’ refers to far more than one or two functions such as libido or other apparent functions which happen to be overanalyzed and overemphasized by many individuals that do not see what is essentially ‘the big picture’. The human body’s physiology and endocrine system are not as abridged and dumbed down as many uneducated anabolic steroid users make it out to be, especially when trivializing the inclusion of Testosterone in every cycle.

Testosterone is a hormone that is vital for proper libido function, it is a regulator of cognitive and physical energy, it serves to regulate the population of thromboxane A2 receptors on megakaryocytes and platelets (and hence platelet aggregation in humans), and it is critical for proper function of mental and psychological processes, as well as a myriad of other crucial physiological functions – so many, in fact, that to cover all of these functions would require a completely separate article. However, the majority of these functions have already been discussed throughout this article, and the absolute importance of Testosterone in every cycle for the purpose of the upkeep of these proper physiological functions should be of no surprise to the reader at this point. Because a certain anabolic steroid is ‘better’ or ‘stronger’ than Testosterone in one or two select areas (namely anabolic tissue increases, which is what every individual overemphasizes), and that it could possibly be more convenient to administer (such as oral-only cycles), absolutely does not mean that it is better than Testosterone in every single aspect and function. The majority of anabolic steroid analogues either do nothing at all or falls very short in providing proper regulation to many of those physiological functions that Testosterone is responsible for regulating and governing. There are in fact a plethora of other anabolic steroid variants that can and do also serve to in fact mitigate (hamper or disable) those functions.

Best Steroids

What are the best steroids? This is a tricky question and one that can’t be answered with a single anabolic steroid. With literally hundreds of anabolic steroids available to us deciding which is the best steroids is difficult. We can however, decide which steroid is best suited for your goals or point you in the right direction. There are a number of factors, which can determine the best steroid for you, the user. Your age, past experience, gender, goals, training experience, weight, level of muscle mass, current health state and genetics. Below we will try to discuss this in more detail and determine the best steroids available and optimally suited.

Best Steroids Overall

There is one anabolic steroid that is the best steroid for overall application and that’s none other than the primary male sex hormone – Testosterone. Testosterone is what gives males their sex drive, muscle mass, wide shoulders, strength gains, confidence and sense of well-being. It’s the alpha-male hormone after all and makes us men. Testosterone is what almost all steroids are derived from including some of the most popular steroids available to us, such as Dianabol, Deca-Durabolin and Dihydrotestosterone (DHT) derived steroids, like Winstrol and Anavar. Testosterone is the best steroid and most popularly used anabolic steroid used and ever used and for good reason. Testosterone is excellent and building muscle and increases fat loss in users when larger exogenous amounts are injected or administered. As well as building muscle and accelerating fat loss, its also one of the best steroids for preserving muscle mass when in a calorie deficit or when dieting. Whether you’re bulking or cutting, Testosterone is often used as a base for the steroid cycle because of these above positive effects, and ability to maintain sexual function and other male characteristics that other anabolic steroids may decrease when used alone.  Testosterone is also widely available and in numerous applications. Oral testosterone, injectable testosterone, testosterone or steroid creams and gels and pellets all give us extra amounts of testosterone when required.

Because testosterone is already in our bodies we have experienced its effects going through puberty (males). Therefore we may have experienced the acne, gynecomastia, mood swings, aggression, hair growth and hair loss, increased sex drive and deepening of vocal chords. Larger amounts of applied testosterone will merely amplify these effects but generally, testosterone is a well tolerated and fairly friendly anabolic steroid.

The Five Basic Stipulations of Proper Steroid Cycles and Responsible Steroid Use

1. No individuals under the age of 24 should engage in any anabolic steroid cycles what so ever.
2. Testosterone must be the very first and the ONLY anabolic steroid used in the very first beginner anabolic steroid cycle, and Testosterone must also be included in all cycles, no exceptions.
3. Cycle lengths should be kept as short as possible.
4. The lowest effective dose in order to provide gains should always be utilized before increasing doses.
5. An absolute minimum of stacked compounds (no more than 2 at any given time unless absolutely necessary) should be used in any given anabolic steroids cycle.

Detailed explanations of the five stipulations:

1. There is no specific age for each and every human that has been determined to be the age by which the human body and its subsystems (especially the endocrine system, which is our primary concern here) have fully matured and developed. The ultimate final age by which we all reach full growth and maturation is determined by our genetics and to a lesser extent, our lifestyle habits. Every individual’s genetic ‘programming’ is different, and therefore some individuals will fully mature at a younger age while others may reach full maturation at approximately 24 years of age, and others will perhaps mature at an even older age. It is general knowledge concerning the endocrine system that Testosterone levels in males are continually rising until the median average age of approximately 24 – 25 years old, at which point these levels reach their peak and begin to decline. The Hypothalamic Pituitary Testicular Axis (HPTA) which controls endogenous natural Testosterone production is a very sensitive network. Furthermore, there is no specific ‘test’ that one might be able to undergo in order to determine if he/she has reached full maturation of the human body’s subsystems. Therefore, the average median age by which almost all human beings reach maturity has been determined to be 24 – 25 years of age. Some may mature earlier (as mentioned earlier) and some later than this. By engaging in anabolic steroid cycles and introducing anabolic steroids to the body prior to the age of 24, the risks of severely and permanently disrupting and damaging the endocrine system is extremely high. Only after the age of 24 – 25 do the risks of considerable and permanent HPTA damage drop drastically.

2. Testosterone is literally the original anabolic steroid, produced naturally within all humans and most animal species. It is considered the safest anabolic steroid one could use for this reason, due to the fact that it is the hormone that each individual’s body already produces, already uses, and is already accustomed to. Therefore, the use of Testosterone for the purpose of performance and physique enhancement is simply the equivalent of introducing more of a hormone into the human body that it already manufactures and uses.

Furthermore, all first cycles for bare beginners to the world of anabolic steroids should always use some form of Testosterone-only as their very first anabolic steroid cycle. Solitarily run Testosterone cycles provide the user with a safe compound (Testosterone) that the human body is already accustomed to naturally, as all humans already produce Testosterone endogenously. This will allow the user to gauge their response to the most basic anabolic steroid, Testosterone. It is from this gauging process that individuals can assess their potential responses to other anabolic steroids, as the chances are that if an individual responds horridly to a basic Testosterone cycle, then there will likely be a higher chance of the individual responding even worse to most other compounds which are essentially modified analogues of Testosterone.

As explained above, solitary Testosterone-only cycles are the ideal beginner first-time anabolic steroid cycles. The problem with stacking multiple compounds in a beginner first-time cycle lies in the fact that it is quite a potentially dangerous practice. A hypothetical beginner who has never used anabolic steroids or whom has never run a cycle before would not know what to expect upon use. It stands to reason that if a stack of several different compounds are run for a first cycle and the individual reacts in a very negative manner (or experiences a particular very undesirable side effect), there will be no possible means for this individual to figure out which anabolic steroid is responsible for the bad reaction if a cocktail of several anabolic steroids have been stacked in one cycle. This would become possibly life-threatening if said reaction were to be a very serious mortal reaction (such as an allergic reaction, for example).

3. Duration of use is an extremely very influential factor but very easily understood, as it need not be explained that the longer a particular anabolic steroid cycle is run, the increased incidence of side effects will also present themselves as the duration of use becomes longer and longer. The recovery of natural endogenous Testosterone production also becomes increasingly difficult following the termination of an anabolic steroid cycle if a cycle is run for longer and longer lengths of time. Various anabolic steroids may exhibit higher degrees of HPTA suppression and shut-down than other compounds, but all anabolic steroids exhibit this effect of HPTA suppression and eventual shutdown as duration of use continues. Severely atrophied Leydig cells in the testes following extremely long cycles will have far greater difficulty re-engaging endogenous Testosterone production again due to desensitization to gonadotropins resultant of long-term suppression/shutdown. Ideal cycle lengths for short-estered anabolic steroids should be in the range of 8 – 10 weeks, and for long-estered anabolic steroids, 10 – 12 weeks. Any longer than this and the individual runs high risk of increasingly difficult HPTA recovery.

4. The issue of utilizing the lowest effective dose is simple: make progress with the lowest possible dose first, grow into this dose, and then increase the dose as required (which is on average, several cycles into beginner use). Many individuals (mostly beginners) tend to engage in extremely ludicrous activity whereby a brand-new first-timer will run 500mg/week on their first cycle, then proceed to 700mg/week on their second cycle, and then 1,000mg/week on their third, and so on and so forth. This is absolutely unnecessary, and, not to mention not very healthy at all. As mentioned earlier, many anabolic steroid users (both beginners and experienced users) severely underestimate the power of these hormones and most usually when individuals do things like that, it is because they claim their gains and progress has stopped. The culprit is usually a flaw in their nutrition or training (or both), not in how many mg per week of total steroid they are using. These details and concerns must be kept in mind. A very important detail for all individuals to understand in relation to anabolic steroid doses is that the human body only manufactures approximately 50 – 70mg weekly of Testosterone (depending on various factors such as age, lifestyle habits, genetics, etc.). Considering this, we can use logic to conclude that: 500mg is approximately 7 – 10 times the amount that the human body produces. Suffice to say, 300mg weekly should then be perfect for any first-time beginner cycle.

5. Quite simply put: the use of more than two compounds stacked in any given anabolic steroid cycle is completely unnecessary for the average casual recreational anabolic steroid user. The stacking of three or more compounds in a single anabolic steroid cycle is only necessary for competitive bodybuilders and professional athletes. Increasing the number of anabolic steroids utilized in a single cycle increases the weekly dose of total steroid, which thereby increases the risk and intensity for side effects tenfold, and presents increasingly harsh stressors on the human body. 

How to Avoid Suppression of Testosterone Production

The classic cycle of anabolic steroids taken within 24 hours (for example, injectable testosterone esters) necessarily lead to a suppression of LH and products, respectively, to the suppression of testosterone production.

There are 3 ways to avoid this:

1) Avoid permanent use of highly-androgenic steroids.
This can be accomplished, for example, using the oral steroid (whose half-life of several hours), half the dose in the morning (eg. at 9 AM), while the remaining half of the dose at approximately at the afternoon (at 12 AM). Even 100 mg per day of Methandrostenolone can be used in this way with a slight suppression of testosterone production.

This is due to the fact that high eroven exogenous (produced outside of) testosterone is kept for 3-4 hours, but this has not been enough to trigger the lowering of its own testosterone level (probably due to the fact that the pituitary and the hypothalamus does not respond only the current level of androgens, but also on past levels of testosterone and this 4-hour hormonal racing roughly be ignored endocrine system). The problem with this approach is that the effect on the growth of muscle mass is not very good compared to when the steroid in the blood constant.

2) Use the number and type of steroid, which will not significantly inhibit the production of testosterone. Primobolan in a dosage of 200-400 mg per week suitable for this purpose. However, in this case, the results of such a cycle would not be comparable to the more substantial cycle. Esters of testosterone (eg. drugs like Sustanon, Omnadren, Test Enanth, Testosterone Cypionate, etc.) and nandrolone decanoate (Retabolil, Deca Durabolin) significantly inhibit the production of testosterone, even at a dose of 100 mg per week, so that the use of these drugs in low dosage does not make sense: testosterone production will be suppressed and quite unsignificant progress will be achieved.

3) Generally, anti-androgens could be used, but it's just completely stop the growth results in a mass and strength.

In those cycles where steroids doses are high enough to effectively increase the results seen an interesting thing. During the first 2 weeks of the cycle only the activity of the hypothalamus is suppressed, and it produces much less LHRH as a result of high levels of steroids.

Activity of the pituitary gland at this time is not suppressed at all: in fact, LHRH receptors are sensitive and will respond to LHRH (if it is produced) even more than usual. However, after two weeks, the activity of the pituitary gland is also suppressed, and even if LHRH is produced, the pituitary will produce little or no produce LH. In this case, there comes a deeper type of suppression of the arc. Apparently, after the suppression of this point, there is no next point, where again the suppression becomes deeper. But over time, the restoration is complicated.

Practically there is no distinction between the use of steroids for 3 weeks and 8 weeks: recovery will take the same time. Between 8 and 12 weeks, it becomes increasingly likely that the recovery will be harder and slower, even though the 12-week cycle typically does not create too many problems, and recovery takes only a few weeks. Cycles longer than 12 weeks can create substantial problems with recovery.

It is not known exactly what changes occur in the hypothalamus and pituitary gland when courses are too long, but in practice it appears that the more the cycle goes for 8 weeks, the longer and more difficult the subsequent recovery. There is a suspicion that what occur violation of the mechanisms of secretion of LHRH hypothalamus.