FitnessDose

Showing posts with label hgh. Show all posts
Showing posts with label hgh. Show all posts

Monday, November 25, 2013

Why Bodybuilders Use HGH And Peptides

GHRP-2, is a synthetic, hexapeptide that has some very potent properties. It is in the class of growth hormone releasing peptides (GHRPs), which act on the hypothalamus and the pituitary gland, to release growth hormone, by appearing through the endogenous ghrelin receptor. It is considered one of the few healthcare means that can be able to reverse the aging effects in adults who are deficient of the growth hormone.

GHRP-2 is known to encourage appetite and hunger. It does this by stimulating the release of Ghrelin, which is also a peptide observed in the stomach, that advertises urge for food and gastric emptying. GHPR-2 is also used for a range of other medical issues, which include, correcting low growth hormone production, and also promoting excess weight gain in the abnormally thin individuals.

GHRP user may report strength raise and improved muscle mass. This is along a much better overall sense of well being and decreased body fat. Neurons are also affected in the same method as they would be by steroids, causing a significant strength raise. For someone who has previously used artificial development hormone, slowing the body's natural production of the same, this peptide can be used to activate the natural production of this growth hormone.

This peptide is also a very suitable compound to use if one is nursing and rehabilitating injuries. It has been shown, clinically, to have a very good effect on connective tissues and tendons regeneration and strengthening. Depending on one's goals, a person may use between 100 - 600mcg per day. For instance, a person looking for some slight raise in sleep quality, or joint and tendon improvement, may stick towards the lower end of this dosage amount. Alternatively, a person seeking to use this peptide for its mass and muscle building effects may ramp up the dosage considerably.

Other benefits of using GHRP-2 include improved sex dr and desire, stomach fat decrease, enhanced energy and vitality, improved skin elasticity and lines elimination. There is also boostd endurance, heart strengthening, enhanced immune system, improved eye sight and vision, increased protein synthesis, enhanced bone density as a consequence of boostd lime scale retention (which also increases bone strength and mineralization), reduced glucose uptake in the liver organ, better liver glucogenesis, and contribution in the direction of pancreatic islets maintenance and function, among others. You can get peptide GHRP-2 online at http://www.genezameds.com/hgh-peptides-c75/ghrp-2-5mg-p430 GenezaMeds.com - we provide the bodybuiding and performance enhancing community top of the line service with products and reliability that you can trust.

Saturday, September 14, 2013

How To Cycle Off From Steroids

Heavy steroid using athletes, particularly weight lifters, bodybuilders, football players, hockey players, shot-putters etc., are subject to many adverse consequences from continuous steroid use without a break. Adverse cardiovascular effects, liver stress, HPTA downregulation, excessive virilization (women) and psychological disturbances or dependency, are some of the major problems that may develop in these individuals. Additionally, users may develop a tolerance for anabolic steroids that can only be overcome by increasing the dosage or by ceasing the use altogether. The latter, of course, is a much healthier course of action than the former.

Coming off of steroids, particularly long-term usage, is certainly not easily done without considerable loss of muscle mass. Additionally, there can be psychological effects that include depression and loss of motivation. For many athletes, especially those with schedules that do not allow prolonged periods away from competition completely coming off of steroids is not considered an option. However, if these athletes knew how to take the right approach they just might be able to cycle off and have a good chance at maintaining much of their physical condition. This could enable them to increase their ultimate potential in their sports as well as their longevity in the competitive arena.

The Strategy
The off cycle regimen must consist of proper drug, nutritional, and training protocols. The primary goals to achieve are the following:

Minimization of protein catabolism

Maintenance of muscle glycogen levels

Maintenance of high-normal red blood cell levels

Minimization of fat deposition

Avoidance of injury, or injury aggravation

Maintenance of healthy attitude and psychological state

Drugs
This is an off steroids cycle and most certainly not an off drugs cycle. In fact, the proper use of non-steroidal drugs is the mainstay of this program and is vital to its success. I will describe the drugs to be used, why they are used, and how they should be used.

Growth Hormone

GH is probably the single most important drug to maintain muscle mass and bodyweight off of steroids. While GH is not known to be great for anabolic effects, it is very effective for anti-catabolism. Anti-catabolism, or minimization of muscle mass loss, is after all what we are most interested in here. GH has an overall anti-proteolytic effect on the body and shifts the body's metabolism away from the utilization of amino acids and glucose for energy, and towards the use of fat. The end result will be a protective effect upon muscle protein and glycogen, and a mobilizing effect upon body fat.

Many bodybuilders have discovered how wonderful GH, at the proper dosages, is in maintaining their muscle mass off of steroids. Former IFBB pro Gary Strydom once commented that he didn't care if the IFBB tested for steroids, as long as they didn't test for GH.

Notice how I said at the proper dosages. That's right, small dosages just won't cut it. For most people a minimum of 4 i.u. a day is required to impart a proper metabolic response in the body. Some may go as high as 18 i.u. a day but at this levels many problems can occur (i.e. edema, nerve impingement).

There probably is no great advantage to taking GH more than once a day, though some may inject twice a day. GH primarily works through its conversion to IGF-1 and the half-life of IGF-1 in the body is plenty long (8-16 hours). So once a day administration will be good enough to maintain pretty constant levels of IGF-1 in the blood. Furthermore, evidence is also mounting that GH breaks down to certain active peptide fragments with specific biological functions (i.e. lipolysis) and that these have prolonged half lives. Therefore, the active lifetime of the intact GH molecule itself in the blood might be pretty irrelevant.

GH is not cheap through most channels. However, good GH can be obtained from Asia at a fraction of the cost (10 - 20%) that it is available elsewhere.

I think I should also mention now that there is a big misconception amongst people as to what the shelf life of GH is, and that most people grossly underestimate it. The Journal of Chemical Technology states that freeze dried GH products (unreconstituted) are quite stable under refrigerated conditions, and a 24-month shelf-life is typical at this temperature. Also, although solutions of GH at neutral pH readily deamidate (lose ammonia group from end of molecule), and storage of the reconstituted product is limited to a few weeks under refrigerated conditions, biological activity is relatively unaffected even after prolonged storage. So the stuff really stays pretty active in the frig for a considerable time. By the way, reconstituted solutions of GH should NEVER be frozen (this will be the death of it)

Insulin (Humalog)

The use of insulin provides a couple of very important functions in the off steroid period. First of all, it helps preserve glycogen storage in the muscle. Steroids are very good at stimulating glycogen storage and this property likely plays an integral part in their performance enhancing benefits. Going off of steroids leads to a reversal of this and the result is muscular weakness, fatigue, and loss of size and bodyweight. The proper use of insulin can help minimize this.

Furthermore, insulin can help to minimize protein breakdown through its anti-proteolytic effects. Insulin is quite potent in regards to its protective effect on muscle protein, unfortunately it also is very potent in regards to its protective effect on maintaining body fat. Insulin therefore has to be used in the proper fashion to maximize the former, and minimize the latter.

The proper usage of insulin requires the fast acting insulin analog known as Lis-Pro insulin, or Humalog. This altered insulin product is available only by prescription. It differs from other insulin in that it is absorbed quickly into the body after subcutaneous injection. The average time to peak blood levels is 90 minutes and generally it is out of your system in 3 to 4 hours.

Humalog is to be taken immediately after training. The physiology of the body after intense training is such that the benefits of insulin can be maximized, while drawbacks are minimized. Muscle insulin sensitivity as well as insulin independent glucose uptake will peak in the 2-3 hours or so after training. In this time, insulin will preferentially stimulate glucose uptake and glycogen synthesis in muscle over fat. Additionally, high insulin levels at this time will help to counteract the catabolic state that exists in muscles right after they have been damaged by training. A discernible improvement in training recovery (less soreness and injury pain) is often noticed by individuals who utilize this technique.

Humalog administration must be followed by intake of simple carbohydrates and protein within 20 minutes. A general rule is one unit of Humalog per ten kilograms bodyweight, and ten grams of carbs and ten grams of protein per unit of Humalog. That sounds like a lot of carbs and protein but it must be ingested. Whey protein is best, and glucose or maltodextrin can be used for the carbs. 5 grams of creatine can also be added as well as well as 5-10 grams of glutamine.

Erythropoietin (EPO)

Erythropoietin (EPO) is a protein hormone secreted by the kidneys and liver that stimulates red blood cell production (erythropoiesis). Red blood cells carry oxygen to the tissues of the body and so obviously are vital to maximal health and athletic performance.

When people take anabolic steroids, particularly some oral ones such as Anadrol, erythropoiesis is stimulated. The result is an increase in the proportion of blood cells in the blood, also known as the hematocrit. This increase in the hematocrit is partially responsible for the energizing and recovery benefits of steroids. It may also contribute to the blood volume and vascularizing effects of anabolics.

When you go off anabolics, the increase in hematocrit gradually subsides and you return to pre-cycle lower levels (or below). This effect will take its toll on your physical condition and ability to train at high intensity. Therefore, administration of exogenous EPO can have obvious benefits in the steroid withdrawing athlete.

In addition to its effect in increasing hematocrit, there is some evidence that EPO has direct anabolic effects. It has been shown in rat studies to substantially increase weight gain and injury repair after surgery. Furthermore, EPO receptors are present on myoblasts (immature muscle cell progenitors) and may have a potential in muscle development and repair.

EPO is sold in recombinant form (rhEPO) for injection. One popular form is called Epogen, and it is made for subcutaneous usage. A safe or starting dosage is usually 20 i.u. per kilogram bodyweight, 3 times/week. After two or three weeks, a maintanence dose of 20 iu/kg BW can be taken once a week. One should wait about two weeks after ceasing steroids to commence EPO therapy to avoid any excessive increases in hematocrit which can be quite dangerous. It is also very advisable to have periodic blood tests that include a hematocrit assay while taking EPO just to be safe. Interestingly, I think that this test is automatically done for free everytime you donate blood, and all you need to do is ask the nurse what your hematocrit is reading (just out of curiosity of course). 

Wednesday, September 4, 2013

HGH Therapy - Adding Vitality to Your Life

Steroids have been controversial ever since these were introduced in the 1950s. Numerous news accounts, mostly on sports figures that tested positive for steroid use, continue to bring negative connotation on these substances. While it is true that some forms of steroids are banned, there are many which are legal (albeit restricted), including the Human Growth Hormone (HGH), also known as Somatotropin. Marketed as Real HGH, Somatropin or 191 Amino Acid Sequence HGH, the biologic drug is available in the US, Europe and other countries. hgh therapy

This HGH hormone is produced naturally in the human body by the pituitary gland and, as its name implies, is responsible for making cells grow bigger and divide more rapidly. HGH also facilitates inter-cellular amino acid distribution and conversion to proteins, which results in muscle build-up. Studies also show that somatotropin reduces carbohydrate usage in the cells and increase utilization of fats, resulting in a leaner body composition.

Humans make HGH throughout their lifetime; a steady growth from the early years until puberty when production of the hormone reaches its peak and the body experiences growth spurts. At the age of forty, the amount of HGH produced by the body starts to decline a phenomenon seen as the main cause of reduced body functions and frailty that comes with old age.

At present, HGH is medically indicated for the following conditions: growth hormone deficiency in adults, children with short stature or kidney failure, and people with HIV and AIDS - to counteract the muscle wasting effect of these conditions. In the US, use of HGH as an anti-aging treatment is prohibited, though in a report last year, CNN found that prescriptions for HGH treatment are on the rise, even if its legal status is fuzzy.

In adults, use of HGH had been shown to increase metabolism, physical and mental energy, muscle mass, libido and bone density as well as normalize cholesterol levels and reduce body fat. Some of the side effects associated with HGH include swelling in arms and legs, arthritis and carpal tunnel symptoms, muscle pain, diabetes and abnormal growth of bones. Weighing the benefits one gets from HSH against the common side-effects, a growing number of endocrinologists have recognized that in many cases, the advantages far outweigh the possible side-effects, particularly for people whose lifestyle has been greatly curtailed as a result of the hormone deficiency. There are many documented instances wherein patients report generally greater signs of vitality, better health and well-being after taking the hormone.

In the US, body builders and other people with active lifestyles routinely use HGH procured either by prescriptions or online purchases. Obviously, these people see the lean muscle development and fat-burning effects of the hormone greater than the risks associated with it. Other important factors that weigh heavily in favor of HGH are its ability to heal muscle - even cartilage- injuries quickly, and the fact that it is undetectable (for now) in current drug-testing tests a boon for athletes who are required to undergo these tests. For years, bodybuilders have known that combining the hormone with testosterone drugs brings better results well-defined muscles, heightened endurance and strength.

While selling of the injectable HGH is restricted in the country, a lot of online suppliers from abroad can ship the drug to US residents without any complications. Usually, the hormone is taken with other performance-enhancing steroids which are also supplied by the online stores.

Wednesday, June 27, 2012

HGH Human Growth Hormone Effects in Bodybuilding

For young athletes under 27 years, human growth hormone (HGH) acts as a powerful anabolic, positively influencing on increase in body size. This applies to length and thickness of the bones, as well as the amount of muscle. In later years the effect of growth hormone is less noticeable, but its ability to some extent, increase muscle mass, as well as significantly reduce body fat, used in bodybuilding.

Effect of growth hormone

    enhances protein synthesis, provides a steady but slow increase in muscle
    strengthens the bone and connective tissue
    improves metabolism
    increased use of fat for energy needs
    increases in liver glycogen
    at speeds up healing of injuries and rehabilitation

The level and stimulators of growth hormone
Receiving a command from the hypothalamus, the pituitary gland produces growth hormone, which is getting into the blood reaches the liver and converted it into the main working material - somatomedin. Number of growth hormone production increases from birth and reaches a peak of about 21 years, with the same slow down in life. During the night may take place before the 10ti releases the hormone into the bloodstream.
For effective training in bodybuilding, prevent injuries and fatigue, normal growth hormone levels is vital. Even better - if we can improve it.

Stimulants
- Good night's sleep
- The state of stressful
    exercise stress
    pain
    a sharp temperature drop
    Hunger - sleep on an empty stomach is useful in many ways

- The use of protein food. The greatest influence on the production of growth hormone has an intake of protein such as arginine (pork, cheese, cottage cheese, nuts).

Obstacles for the development and effectiveness of HGH can be:

- Exhaustion of the nervous system
- Violations of the liver
- High levels of cortisol
- Receipt of carbohydrate foods