FitnessDose

Thursday, April 24, 2014

Testosterone Recovery After Deca Durabolin

When it comes to negative side effects associated with anabolic steroids, some are far worse than others. Deca Durabolin, perhaps one of the most popular anabolic steroids ever used, and still widely used, is known as mild compared to other commonly used androgens. The parent hormone is Nandrolone and is found in both Deca Durabolin and NPP (Nandrolone Phenylpropionate) and it doesn’t seem to come across as a harsh hormone to use from years of medical data and reports from steroid users. Acne, hair loss, aggression, increases in blood pressure and drastic changes in lipids, kidney function and liver values are not usually attributed to Deca Durabolin use. But there is one side effect that it exerts significantly, and that’s testosterone suppression or inhibition.

When an athlete or bodybuilder uses anabolic steroids, endogenous testosterone function will decrease from use. Different compounds effect testosterone production to varying degrees, but Nandrolone, or Deca-Durabolin is perhaps the most powerful of all commonly used anabolic steroids with Trenbolone. “Deca dick” is a known side effect or slang term given to erectile dysfunction, which has affected a large degree of steroid users and questions spear on large steroid forums daily. Due to the speed of which Deca can suppress natural testosterone production recovery post cycle can be harder than most steroid cycles not containing Deca Durabolin.

Today we’re going to look at a study that looked at 21 men who had been taking Nandrolone Decanoate (Deca Durabolin) and their recovery efforts after coming off of anabolic steroids. The study was conducted in Sweden at the Karolinska Institutet. The researchers found the subjects through an anti-doping hotline setup to help steroid users in Sweden. They state that the participants had “a genuine will to stop using anabolic steroids.”

Deca Durabolin is Nandrolone with the Deconoate ester attached allowing it to stay active for 21 days; however, its metabolites are present far longer in the body. 19-norandrosterone and 19-noreticholanolone appear to remain active for months after use, this may shed light on why its so hard to recover natural testosterone levels. Deca is also known to last in an athletes blood for over 12-16 months which makes it a very bad choice for athletes or bodybuilders in tested sports.

Importantly, the Swedes also tested levels of leutinizing hormone (LH) and follicile stimulating hormone (FSH). LH and FSH are responsible for stimulating the testes (leydig cells) to secrete testosterone. In the figure above you’ll see that LH and FSH were still rising over 12 months after Deca-Durabolin cessation, confirming reports its one of the hardest anabolic steroids to recover from.

Limitations are that this study did not state a post cycle therapy (PCT) was used by any of the steroid users. This is where anti-estrogen use helps the body reover from a steroid cycle. We recommend all steroid users conduct a full PCT after using anabolic steroids whilst combining them with an aromatase inhibitor and also human chorionic gonadotropin (HCG) to help maintain testicular size and function. HCG is suggested at 250-500ius per week or every 3-4 days. If side effects occur, or testosterone recovery isn’t possible or problematic, seek the guidance of a physician or endocrinologist.

Tuesday, April 15, 2014

HCG Human Chorionic Gonadotropin

Human Chorionic Gonadotropin (HCG) is what is known as a protein hormone (or a peptide hormone) that is naturally and endogenously  produced by the female human body by the syncytiotrophoblast cells in the placenta. In females, HCG plays a very important role in stimulating the release of Progesterone, which is a hormone vitally essential for pregnancy. HCG that is bottled for human use is not synthesized in creation, but is instead obtained from humans. Specifically, it is found in very high concentrations in pregnant females as previously stated. HCG is in fact what is used as the number one primary indication of pregnancy in females, as it is only present in very, very high quantities in females during pregnancy. HCG is what the home pregnancy tests detect in urine, and if present in significant quantities, the home pregnancy tests will turn blue. In women who are pregnant, HCG increases in the body rise very rapidly, and can be detected within 7 days of increased secretion in the body. At this time period, however, HCG levels are only beginning to rise, and blood plasma levels of HCG do not actually peak until approximately 2 – 3 months into pregnancy. Following this 2 – 3 month period, HCG levels then begin to decline.

HCG itself could technically be considered synthetic LH (Luteinizing Hormone) and FSH (Follicle Stimulating Hormone), but the truth is that HCG is indeed a different hormone, but in men it will mimic the actions of LH and FSH identically. LH and FSH are gonadotropins manufactured and secreted by the pituitary gland, and these two hormones in men signal the Leydig cells in the testes to begin or increase the manufacture of Testosterone. The term ‘gonadotropin’ refers to any compound or hormone that stimulates the gonadal organs (testes in men, ovaries in females). In females, LH and FSH trigger ovulation (the manufacture of eggs in the ovaries). HCG, because it is essentially a mimic of LH and FSH in terms of its physiological activity, is administered medically to females that suffer from infertility (perhaps because they do not endogenously manufacture sufficient levels of gonadotropins as it is or for other reasons). Within medicine, HCG is also administered to males for the treatment of hypogonadism (deficient androgen production). It is also used medically for the treatment of pubertal delay in adolescent males, as well as prepubertal cryptorchidism, which is a condition in which an individual’s testicles have improperly descended (either during or after puberty). Among the anabolic steroid using bodybuilders and athletes, HCG has been utilized for a long time for its ability to restore endogenous Testosterone production following the termination of an anabolic steroid cycle. This is a period in which hormonal restoration is imperative, and HCG is normally inserted into a multi-compound protocol of approximately 4 – 6 weeks after an anabolic steroid cycle has ended, and this is known as PCT (Post Cycle Therapy).

Despite what rumors one may hear, HCG is ineffective for fat loss, and holds no capabilities in stimulating the thyroid gland to manufacture more thyroid hormone. This must be made especially clear due to the fact that for a long time, HCG was utilized wrongfully and mistakenly to treat obesity, with the origins of this practice coming from a wrongfully interpreted study in 1954. This study claimed that test subjects had lost significant amounts of body fat following the use of HCG while on a severely low caloric deficit (500 calories daily). Many interpreted the study wrongfully, and focused solely on the fact that HCG was utilized without any thought for the caloric deficit used in the subjects. More than 30 years later, the whole study and HCG-centered medical treatments for obesity were reviewed, and the approved use for the treatment of obesity was eliminated.

Little did people know that the severe caloric restriction caused individuals to lose important lean tissue mass (muscle) as well as important organ tissue in order to preserve itself, and that this result of severe caloric deficits were worse on the body than obesity. Eventually the FDA in 1974 had even issued a statement on all pamphlets that were packaged with HCG that made it very clear that the use of HCG for fat loss is ineffective and should not be used as such.

Today HCG is still widely utilized in medicine, and is widely available on all markets internationally under various major brand names (Pregnyl by Organon, Profasi by Serono and Novarel by Ferring, as well as many others) including an abundance of generic HCG as well.  HCG is a non-controlled substance in almost all countries in the world, including in the United States (although it is still only obtainable by prescription there, it is not a controlled substance). Because of its immense popularity, overabundance on the market, and ease of manufacture, counterfeits and fakes are not an issue.

Chemical Characteristics of HCG
Human Chorionic Gonadotropin (HCG) is a protein (or peptide) hormone, but it is more specifically referred to as an oligosaccharide glycoprotein (a protein molecule that contains one or more carbohydrates/sugar molecules affixed to it as well). Its protein structure consists of an amino acid chain of 244 amino acids, with a sub-unit of 92 amino acids on it that is 100% identical to LH and FSH. It is this subsection of the HCG molecule that enables it to mimic the action of LH and FSH 100% identically on the same receptors in the cells that LH and FSH activate.

Friday, March 28, 2014

The 14 Week Anabolic Steroid Drug Cycle of an IFBB Professional Bodybuilder

While Generation Iron may not address drug use in the sport of professional bodybuilding, one bodybuilder known for openly discussing anabolic steroid administration is Victor Martinez. This tells us that WE MAY get a little advice on anabolics, again I am sure nothing too in depth but maybe enough to open our minds to top bodybuilding cycling methodologies. Here’s a quote from Wayne Demilia, President of the International Federation of Body Builders (IFBB). He said, as quoted from the New York Times May 13, 2001: “When my guys tell you it costs more than $25,000 to get ready for a big contest, do you think they’re talking about pasta?"

As the following Generation Iron - Mr. Olympia style drug cycle commenced, our Pro bodybuilder interviewee was 14 weeks out from the world’s most prestigious bodybuilding event, the Mr. Olympia. Upon beginning this cycle he weighed a whopping 280 pounds. Due to the possibility that he could be identified, his contest weight and his placement at the event will not be published. Below is his cycle.

I know it’s more reminiscent of an old school cycle but I honestly would not doubt that many pro bodybuilders are still following the concept of low dose cycles in order to avoid strong muscle wasting hormones build up when quitting cold turkey prior to competition. Think of it like someone trying to quit smoking a pack a day all at once without scaling down to lesser smokes per day. The withdrawal is intense because all the neurotransmitters that were boosted during smoking drop dramatically once the nicotine leaves the body. Same goes with anabolics, once you stop taking them, the hormones that cause destruction of muscles rise to compensate for the prolonged period of muscle building hormones occupying all the muscle tissues.

Week 14
200 mg/wk methenolone enanthate
25 mg/day methandrostenolone
Total weekly androgen dose: 775 mg

Week 13
400 mg/wk Testosterone
200 mg/wk methenolone enanthate
25 mg/day methandrostenolone
0.70 mg/day tiratricol
3 IU growth hormone M, W, F
Total weekly androgen dose: 775 mg

Week 12
300 mg/wk Testosterone
300 mg/wk methenolone enanthate
5 mg/day methandrostenolone
0.70 mg/day tiratricol
3 IU growth hormone M, W, F
Total weekly androgen dose: 775 mg

Week 11
300 mg/wk Testosterone
300 mg/wk methenolone enanthate
25 mg/day methandrostenolone
0.70 mg/day tiratricol
3 IU growth hormone administered M, W, F
Total weekly androgen dose: 775 mg

Week 10
200 mg/wk Testosterone
400 mg/wk methenolone enanthate
25 mg/day methandrostenolone
0.70 mg/day tiratricol
3 IU growth hormone administered M, W, F
Total weekly androgen dose: 775 mg

Week 9
152 mg/wk trenbolone hexahydrobenzylcarbonate
200 mg/wk nandrolone decanoate
200 mg/wk methenolone enanthate
200 mg/wk dromostanolone
1.05 mg/day tiratricol
3 IU growth hormone, change to daily injections here until Mr. Olympia
Total weekly androgen dose: 752 mg

Week 8
152 mg/wk trenbolone hexahydrobenzylcarbonate
200 mg/wk nandrolone decanoate
200 mg/wk dromostanolone
200 mg/wk methenolone enanthate
3 IU/day growth hormone
1.05 mg/day tiratricol
Total weekly androgen dose: 752 mg

Week 7
152 mg/wk trenbolone hexahydrobenzylcarbonate
200 mg/wk nandrolone decanoate
200 mg/wk dromostanolone
200 mg/wk methenolone enanthate
4 IU/day growth hormone
1.05 mg/day tiratricol
Begin alternating daily dose of 30 mcg clenbuterol and 100 mg ephedrine (i.e. one day C, next day E)
Total weekly androgen dose: 752 mg

Week 6
100 mg Testosterone suspension administered twice per week
100 mg injectable stanzozolol administered three times per week
228 mg/wk trenbolone hexahydrobenzylcarbonate
200 mg/wk dromostanolone
5 IU/day growth hormone
1.05 mg/day tiratricol
Alternating daily dose of 30 mcg clenbuterol or 100 mg ephedrine (i.e. one day C, next day E)
25 mg/day oxandrolone
Local injections with formyldienolone begin here until Mr. Olympia (upper chest, biceps, and side delts)
Total weekly androgen dose: 1,103 mg*

Week 5
50 mg nandrolone phenpropionate administered twice per week
100 mg Testosterone suspension administered twice per week
100 mg injectable stanozolol administered three times per week
228 mg/wk trenbolone hexahydrobenzylcarbonate
200 mg/wk dromostanolone
5 IU/day growth hormone
1.05 mg/day tiratricol
Alternating daily dose of 30 mcg clenbuterol or 100 mg ephedrine (i.e. one day C, next day E)
25 mg/day oxandrolone
Local injections with formyldienolone (upper chest, biceps, side delts)
Total weekly androgen dose: 1,203 mg*

Week 4
100 mg nandrolone phenpropionate administered three times per week
200 mg/wk dromostanolone
100 mg Testosterone suspension administered three times per week
100 mg injectable stanozolol administered three times per week
1.05 mg/day tiratricol
Alternating daily dose of 30 mcg clenbuterol or 100 mg ephedrine (i.e. one day C, next day E)
25 mg/day oxandrolone
5 IU/day growth hormone
Local injections with formyldienolone (upper chest, biceps, side delts)
500 mg/day testolactone
500 mg/day tolbutamide
100 mg/day mesterolone
Total weekly androgen dose: 1,975 mg*

Week 3
100 mg nandrolone phenpropionate administered three times per week
200 mg/wk dromostanolone
100 mg Testosterone suspension administered three times per week
100 mg injectable stanozolol administered three times per week
1.05 mg/day tiratricol
Alternating daily dose of 30 mcg clenbuterol and 100 mg ephedrine (i.e. one day C, next day E)
25 mg/day oxandrolone
5 IU/day growth hormone
Local injections with formyldienolone (upper chest, biceps, side delts)
500 mg/day testolactone
500 mg/day tolbutamide
100 mg/day mesterolone
Total weekly androgen dose: 1,975 mg*

Week 2
50 mg nandrolone phenpropionate administered twice per week
100 mg/day mesterolone
1.05 mg/day tiratricol
100 mg injectable stanozolol administered three times per week
100 mg/day Testosterone suspension
600 mg/day testolactone
500 mg/day tolbutamide
750 mg/day aminoglutethimide
Alternating daily dose of 30 mcg clenbuterol or 100 mg ephedrine (i.e. one day C, next day E)
25 mg/day oxandrolone
5 IU/day growth hormone (GH stops this week)
Local injections with formyldienolone (upper chest, biceps, side delts)
Total weekly androgen dose: 1,975 mg*

Week Preceding the Mr. Olympia
50 mg nandrolone phenpropionate administered twice this week
100 mg/day mesterolone
100 mg injectable stanozolol Monday, Wednesday, and Friday
100 mg Testosterone suspension Saturday, Tuesday, Thursday
600 mg/day testolactone
500 mg/day tolbutamide
25 mg/day oxandrolone
Alternating daily dose of 30 mcg clenbuterol or 100 mg ephedrine (i.e. one day C, next day E)
750 mg/day aminoglutethimide
Local injections with formyldienolone (upper chest, biceps, side delts)
Total weekly androgen dose: 1,575 mg*
Total androgen dose for 14 week cycle: 15,937 mg*
*Androgen totals do not include site injections of formyldienolone or oral administration of testolactone.”

Friday, March 14, 2014

GP Methan 50 Dianabol by Geneza Pharmaceuticals

Dianabol is one of the most popular anabolic steroids of all times. The very first oral anabolic steroid synthesized, Dianabol was created as a means to aid the U.S. Olympic Team athletes who had been dominated by the Soviet Union athletes due to their use of the powerful testosterone hormone. What would come is one of the most powerful and effective anabolic steroids ever created to date and with its power it has since its inception remained high in demand. A favorite among competitive bodybuilders for its ability to add raw strength and size, Dianabol since its creation has found its way into the cycles of athletes and gym rats for a multitude of purposes.

The Benefits of GP Methan (Dianabol)

Dianabol was developed for the use in athletics which gives it somewhat of a special purpose as many steroids were first developed for medical purposes outside athletic circles. Being as this steroids intentions were designed for an athlete, particularly regarding strength and performance its benefits will translate perfectly to meet this end.

The most pronounced benefit of GP Methan (Dianabol) is in its ability to increase fat free mass and it is for this reason it has been a staple in competitive bodybuilding for decades. By increasing both protein synthesis and glycogenolysis as we discussed; while most anabolic steroids increase protein synthesis the rate in-which Dianabol increases glycogenolysis is quite powerful; in simplistic terms this means your carbohydrate intake becomes more valuable and this is why so many choose to use this steroid when in a bulking or gaining phase. This raw energy in-which it provides will also translate into increasing strength but we must not neglect to understand Dianabol dramatically increases nitrogen retention as well, which in effect again will promote both size and strength. While many anabolic steroidal hormones also carry this nitrogen effect Dianabol will cause the individual to hold more nitrogen in his muscle tissue than most other anabolic steroids.

Those who use GP Methan (Dianabol) will find increases of 20-30lbs to be very common place when diet and exercise are appropriate to meet such an end. However, as is with most steroids Dianabol can serve a multitude of purposes, although its primary purpose will be while bulking. Many competitive bodybuilders use GP Methan (Dianabol) during their contest prep cycle; this practice is largely done in order to maintain strength so that one may push through training while on a calorie restricted diet. Further, because of the attributes associated with this steroid the athlete will enable his body to preserve more lean tissue while on a calorie restricted diet.
The Side-Effects of GP Methan (Dianabol)

While Dianabol can be toxic to liver, as we discussed the effects are largely reversible assuming responsible use is applied. However, while a toxic effect remains a concern the most prominent negative side-effect will in-fact be that of increased blood pressure. Those who suffer from existing high blood pressure are highly cautioned against using this steroid until the problem is under control. While issues of increased blood pressure are the most common of all negative side-effects associated with this steroid many will find that even high doses of the steroid affect their blood pressure very little to not at all; it is impossible to predict where you will fall. Beyond blood pressure aromatase is something one will need to keep an eye on as estrogenic related side-effects such as Gynecomastia can occur. For this reason responsible use will normally include an aromatase inhibitor such as Arimidex or Letrozole. Last but certainly not least, Dianabol will suppress your natural testosterone production and most will find in order to use this steroid exogenous testosterone must be applied if we are to keep adequate levels of testosterone in the body. However, as most will greatly benefit from using both anabolic steroids Dianabol and Testosterone together in a stack for most this will be of little concern.
GP Methan (Dianabol) & Anadrol

Dianabol and Anadrol are often mentioned together in an anabolic steroid discussion and as both are powerful orals apt towards strength and size it’s easy to understand why. In many circles Anadrol is often viewed as the more powerful choice but this is simply not true. Milligram for milligram Dianabol is much stronger than Anadrol but the misconception exists for one reason; most will take in far more Anadrol than Dianabol; common Anadrol cycles are upwards of 100mg while common Dianabol cycles are as little as 30mg. Make no mistake, both steroids will get the job done and some will find they tolerate one over the other but this doesn’t change the truth, as Dianabol is the most potent mass building oral steroid on the market.
Dianabol Cycles & Doses

As GP Methan (Dianabol) is most apt for strength and size it is in a bulking cycle where it will be primarily used; it can be used in a cutting cycle as we discussed above but it is in bulking we will focus on as this is the primary purpose. Dianabol is a very fast acting steroid with a very short half-life to indicate as much. Dianabol carries a half-life of approximately 5 hours, making it one of the fastest acting and short duration oral anabolic steroids anyone will ever use. Due to its almost instant effect most will find using this steroid at the beginning of a cycle to be highly effective as a means to kick start the cycle. While kick starting is common place Dianabol can be used later in a bulking cycle in order to break through a plateau when gains begin to halt; many competitive bodybuilders will run Dianabol in two phases during one cycle, as a kick start and as a plateau buster.

As for dosing, there is nothing set in stone but 20mg will prove to the minimum in order to see true results with 100mg being the max most any advanced Dianabol user will ever want to undertake. While 100mg can be used safely most will find 50mg of Dianabol to be all they ever really need; assuming their product is real as there is a massive amount of low dosed Dianabol on the black market. For the beginner a dose of 30mg is generally recommended as it will give you the boost you need but low enough to ensure problems that may occur are manageable. As with all anabolic steroids it is important to keep the dosing very low in the beginning in order to determine how you will react and how well you tolerate the particular compound. Granted, for many a low dose may be all you ever need and in the case of Dianabol, as it is very powerful, low dosing may be perfect for you.

Friday, February 28, 2014

Properties of Deca Durabolin

Deca Durabolin is the trade name for the injectable anabolic steroid Nandrolone Decanoate. It is simply the anabolic steroid Nandrolone with the long ester Decanoate attached to it in order to augment release times and the half-life of the drug. Other formats of Nandrolone exist as well, such as Nandrolone Phenylpropionate, also known by its trade name Durabolin or NPP (Nandrolone with a Phenylpropionate ester attached). However, ‘Deca’ as it is colloquially known, is the most common and most popular form of Nandrolone.

Properties of Deca Durabolin

Nandrolone is a stronger anabolic steroid than Testosterone, but not by a great deal. Nandrolone possesses an anabolic rating of 125, while Testosterone holds an anabolic rating of 100. Nandrolone’s favorability lies in its very low androgenic rating of 37, while Testosterone holds an androgenic rating of 100 – quite significant compared to the androgenic strength of Nandrolone. The lower androgenic activity of Nandrolone is due in large part to the fact that Nandrolone converts into Dihydronandrolone, which is known to be a much less potent androgen. Nandrolone possesses very low Estrogenic activity and binds very poorly with the aromatase enzyme, which is the enzyme responsible for the conversion of androgens into Estrogen. It is estimated that only approximately 20% of Nandrolone is converted into Estrogen in comparison with Testosterone’s conversion rates[2]. This is due in very large part to the fact that Nandrolone is a Progestin (as are all 19-nor compounds)[3]. The other major factor in this is the fact that Nandrolone can undergo Estrogen conversion in the liver, but other locations where there is a high rate of Estrogen conversion (such as fat tissue), Nandrolone is quite resistant[4]. Progestins are very resistant to Estrogen conversion, but the fact that Nandrolone is a Progestin presents various issues itself.

Nandrolone lacks the 19th carbon that Testosterone possesses, which makes it a Progestin and it has been demonstrated that 19-nor anabolic steroids tend to exhibit binding affinity for the Progesterone receptors in the body[5]. As mentioned above, this presents some issues that are not commonly seen with other anabolic steroids that are not Progestins. Nandrolone is considered to possess moderate Progestogenic activity. Progestogenic side effects are almost identical to Estrogenic side effects, and they include: severe endogenous Testosterone production shutdown/suppression, gynecomastia, and water retention. It has been discovered that the activity of Progestins is closely correlated with the activity of Estrogen in the body. There also exist some side effects associated with Progestins that are not seen in other anabolic steroids.

19-nors being Progestogenic compounds are known to increase a hormone in the body known as Prolactin. Prolactin levels above normal in men often results in side effects such as lactating nipples, erectile dysfunction, anorgasmia (inability to achieve orgasm) and endogenous Testosterone production suppression/shutdown. An interesting point to learn is the fact that Progesterone itself is known to inhibit Prolactin production, and that 19-nors such as Nandrolone and Trenbolone being classified as Progestins should serve to actually suppress Prolactin levels. However, this is not the case as Nandrolone and Trenbolone are not Progesterone themselves – they are anabolic steroids that exhibit Progestogenic activity due to their chemical modifications and it is therefore very possible for these hormones to exhibit activity that is contrary to the activity of a similar hormone or parent hormone. It has been found that Nandrolone and Trenbolone can and do in fact increase Prolactin levels in the body.

Prolactin increases can be controlled either with the use of Prolactin antagonist drugs (such as Cabergoline or Pramipexole), however, prevention of rising Estrogen levels are also an effective method. For one thing, it is strongly speculated that the Estrogen in fact serves as a co-binding factor in the Prolactin receptor expression (PRLR). This can increase an individual’s sensitivity to Prolactin even if Prolactin levels themselves are not high in the body. This is a very sound theory when it is understood that the Estrogen receptor is a causative factor in Prolactin issues. Therefore, controlling Estrogen levels should control the effects of Prolactin. This is the number one reason why the side effects associated with 19-nor compounds (such as Nandrolone and Trenbolone) are frequently reported to be far more pronounced and with greater severity when they are used in a high Estrogen environment (whether it is from stacking Nandrolone or Trenbolone with high aromatizable doses of an aromatizable compound, such as Testosterone or otherwise).

It is because of the Progestogenic nature of Nandrolone that it is known to produce severe endogenous natural Testosterone production suppression and shutdown. Therefore, it is recommended that at all times whenever using Deca-Durabolin in a cycle that Testosterone be utilized with it in order to maintain normal physiological function of Testosterone in an environment in which natural Testosterone production has halted or been severely lowered.

Thursday, February 13, 2014

Testosterone Cypionate by Accordo RX

Testosterone Cypionate is one of the most popular forms of testosterone the world over and the most commonly used testosterone in hormone replacement therapy in the United States. A very powerful anabolic and androgenic hormone, Testosterone Cypionate is equal in both regards and is one of the most efficient and effective hormones we can use for almost any purpose. To understand Testosterone Cypionate we only need to understand the hormone testosterone and once we do we can understand how the various esters available, in this case Cypionate affect its mode of action.

Testosterone is a hormone naturally produced by both men and women responsible for a host of functions; most notably muscle and bone growth, regeneration and male sexual characteristics. While men produce nearly ten times as much testosterone as women both require adequate amounts of this androgen class hormone in order to maintain a proper endocrine system. For those who suffer from low levels of testosterone, as Testosterone Cypionate by Accordo RX is a pure form of testosterone it is often used to combat this condition and return levels to a more suitable level. Those who suffer from low testosterone levels commonly find their libido to be reduced, fat gain and muscle loss to occur, as well as immune system deficiencies and even depression. As you can easily see testosterone is a very important hormone and with its many functions, when we increase levels beyond a normal range, as is the purposes in performance enhancing we effectively increase the attributes associated with this powerful anabolic androgenic steroid.

By its mode of action Testosterone Cypionate increases both nitrogen retention in the muscles as well a protein synthesis; increases red blood cell mass and blocks and reduces muscle wasting hormones such as cortisol. Further, by its ability to increase IGF 1 production in the body, Testosterone Cypionate becomes even more anabolic in effect when administered in a fashion that increases levels to a performance enhancing range.

As a testosterone based hormone attached to the Cypionate ester, Testosterone Cypionate has a half-life of approximately 12 days. This is a fairly long half-life and is generally the longest half-life of any commonly used single ester form of testosterone. Because it has a long ester attached in the Cypionate form the effects of this steroid will last a very long time; for example, 200mg of Testosterone Cypionate will yield an active 100mg of testosterone even 12 days after the last injection; of course assuming one is administering the hormone more often than every 12 days the total amount will be much higher but vary depending on the total dose.
The Benefits of Testosterone Cypionate

The benefits of Testosterone Cypionate are truly immense and provide every trait one would be after through the use of anabolic steroids. By its mode of action Testosterone Cypionate has the ability to increase both strength and size to a large degree which is by-in-large the principle desire of any anabolic steroid user. Further, because increased lean tissue improves our metabolic rate and because Testosterone Cypionate affects muscle wasting hormones in a positive manner body-fat is often reduced when the steroid is used.

You need to understand, using Testosterone Cypionate will not automatically lead you to gaining massive amounts of muscle tissue on its own; if a large muscular physique is what you are after you have to feed it but by doing so in conjunction with testosterone therapy we increase the efficiency of the food we are eating which can lead to a more muscular physique. Further, in the same light yet in the opposite direction, those who are after a leaner physique find Testosterone Cypionate to be a perfect choice as its mode of action aids in preserving lean muscle mass when on a calorie restricted diet. Plus, when dieting, the more muscle mass we can hold onto the greater our metabolic rate will be, the greater our fat-loss will be and the more pleasing our physique will be in the end.

The Side-Effects of Testosterone Cypionate

All medications, hormones and non-hormones, steroidal and non-steroidal alike carry with them the possibility of negative side-effects, even Aspirin and Testosterone Cypionate makes no exception. However, when used by healthy adult men and when used responsibly many of these side effects can largely be avoided and the individual will only enjoy the positive benefits.

The most common side-effects brought on by Testosterone Cypionate are of an estrogenic nature. Testosterone will convert to estrogen through the aromatase process and can bring about such negative effects such as Gynecomastia, water retention, blood pressure and cholesterol issues to name a few. Further, while we can largely prevent these side-effects from occurring there is one side-effect that is assured; testicular atrophy. When we administer Testosterone Cypionate we are taking in a synthetic testosterone and by doing so our body no longer requires its own natural production. Since testosterone is produced in the testicles, once production comes to a halt the testicles shrink; however, once use is discontinued and production begins again they will return to their normal size.

There is a strong risk to reward ratio in play when using Testosterone Cypionate and generally all anabolic steroids; the more you use the greater the benefit but the more you use the greater the risks. While this is a reality, regardless of the amounts you use there are things we can do to avoid nasty side-effects brought on by the aromatase process. The use of an aromatase inhibitor (AI) will greatly reduce your chances of Gynecomastia and will greatly aid in unwanted water retention; further, as controlling estrogen in this manner will aid in keeping cholesterol and blood pressure stable it really doesn’t make any sense not to use an AI. However, even with an AI water retention will occur in those who eat more carbohydrates than they need; this is mentioned simply because many blame testosterone on their water retention when bulking when the truth is they are simply overeating. Further, through sound dieting principles, even when bulking, supplementing with fatty acids can largely control your cholesterol and is strongly advised if testosterone is going to be used.

Friday, January 31, 2014

Sustanon 250 Testosterone Blend by Biomex Labs

Sustanon 250 Testosterone Blend by Biomex Labs composition of the compound is as follows:

    Testosterone Propionate: 30mg
    Testosterone Phenylpropionate: 60mg
    Testosterone Isocaproate: 60mg
    Testosterone Decanoate: 100mg

To understand Sustanon 250 we only need to understand testosterone and the manner in-which esters work. Once we understand the hormone testosterone and once we understand the esters attached are not hormones then we can understand how this particular steroidal compound is supposed to work.

As you can see from its makeup a large portion of the testosterone becomes active very quickly once administered due to the Propionate and Phenylpropionate forms being attached. However, the full release will not occur until the Decanoate fulfills its function; because of the Decanoate ester being attached Sustanon 250 has a total half-life of approximately 18 days.
The Benefits of Sustanon 250

The greatest benefit of use is by far the ability to provide testosterone over an extended period of time but for the performance enhancer this proves to be of little use. When used for performance purposes the idea is not to simply provide testosterone but to do so and keep it at its peak level as well as stable. Due to this fact and since Sustanon 250 provides a dose that dwindles as time goes by for performance purposes it must be injected at minimum every three days with every other day being optimal.

Once you understand the manner in-which best suits your needs in-terms of injection frequency you can then enjoy the benefits of this powerful testosterone hormone. Like all testosterones, regardless of the form, Sustanon 250 will greatly increase nitrogen retention in the muscles as well as protein synthesis; key factors in both growth and preservation. Further, through testosterone use we can readily increase our red blood cell count and the powerful anabolic IGF 1 hormone, all key factors in the performance game.

The Side-Effects of Sustanon 250 Testosterone Blend
All medications, steroidal and non-steroidal alike carry with them possible negative side-effects, Sustanon 250 makes no exception. The possible side-effects of Sustanon 250 are identical to every other testosterone form as the active hormone testosterone is what comprises Sustanon 250. As testosterone, regardless of form converts to estrogen via the aromatase process common anabolic side-effects of an estrogenic nature can occur such as Gynecomastia, increased blood pressure, as well as cholesterol issues and testicular atrophy. While testicular atrophy occurs in all who use testosterone it will reverse once use is discontinued when used responsibly. Testicular atrophy occurs because by administering exogenous testosterone our bodies are no longer required to produce their own; as testosterone is produced in the testicles, once production comes to a halt they simply shrink; once production begins again they return to their normal size. Beyond testicular atrophy, which will assuredly occur, other common side-effects are easily avoidable. As most side-effects are due to estrogen conversion by taking an aromatase inhibitor in conjunction with our testosterone we can prevent the estrogen from binding as well as reduce the amount in the body. Further and most importantly, with proper diet rich in healthy fats we can largely protect against blood pressure and cholesterol issues.

Testosterone Blend
Sustanon 250 is not the only testosterone mixture on the market; there are actually quite a few with Omnadren and Testoviron being the two most prominent besides that of Sust. Generally everything that can be said of Sustanon 250 can be said of Omnadren as they are almost identical in every way and while Testoviron is simply a mixture of Testosterone-Enanthate and Testosterone-Propionate made by Schering (Not to be confused with Testoviron Depot, an Enanthate only form) there is something you need to understand. Of all testosterones and testosterone forms, testosterone mixtures are by-in-large the most commonly counterfeited on the black market. The demand for such mixtures is often high because certain labs prey on the ignorance of others; many believe a testosterone mixture is more powerful than a single-ester form when as you understand mixing various forms together does not change the active hormone. Understand, testosterone is simply testosterone regardless of the form and regardless of how many forms you couple together.

Sustanon 250 Cycles & Doses
Sustanon 250 can be used for any cycle be it bulking or cutting and as most steroid users will build their cycles around testosterone Sust can be a fine choice. Testosterone is generally well-tolerated by healthy adult men who use it; as it is a hormone naturally found in our body it is not one we are unaccustomed to and in healthy adult men increased levels are often well received. Further, when stacking various anabolic androgenic steroids together, because our natural production of testosterone will cease it is important to keep some testosterone in the body for proper physical function and when you add in the beneficial anabolic characteristics it simply makes sense. Regardless of how you plan your cycles testosterone will in most cases necessarily be a part of them all and in many cases the only steroid you’ll ever need.

For the individual who uses Sustanon 250 as part of a testosterone replacement plan 250mg every 2-4 weeks is a common dose but this will be determined by your doctor. For the performance enhancer, as a general rule of thumb 500mg of testosterone is often considered the base dosing level and is perfect for any beginner. While this is a perfect beginners dose many will find it is all they ever need no matter how advanced they become. For the hardcore, doses of 1,000mg per week are fairly common place and even beyond in bodybuilding circles, particularly those who fall in the realm of competition. Understand, when the dose increases, while the rewards may as well so do the risks associated.

Many will find 12-16 week cycles of Sustanon 250 to be perfect and very well-tolerated in most cases; however, a solid post cycle therapy (PCT) plan is necessary once discontinued. Because Sustanon 250 carries long esters you will necessarily begin PCT 3 weeks after your final Sust administration which may include hCG, Nolva and/or Clomid. Those who use hCG are advised to begin use approximately ten days before Nolva/Comid for approximately ten days of use.